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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFAT5
All Species:
18.48
Human Site:
S738
Identified Species:
45.19
UniProt:
O94916
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94916
NP_006590.1
1531
165763
S738
L
S
Q
L
T
E
A
S
Q
Q
Q
Q
Q
S
P
Chimpanzee
Pan troglodytes
XP_001168930
1803
192592
S1011
L
S
Q
L
T
E
A
S
Q
Q
Q
Q
Q
S
P
Rhesus Macaque
Macaca mulatta
XP_001093880
1771
191129
S979
L
S
Q
L
T
E
A
S
Q
Q
Q
Q
Q
S
P
Dog
Lupus familis
XP_546854
1480
160645
S710
I
S
S
N
I
F
P
S
P
N
S
V
S
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV30
1225
132174
G459
L
H
S
C
S
V
K
G
E
E
E
V
F
L
I
Rat
Rattus norvegicus
NP_001100895
1548
167188
E751
V
N
L
S
Q
L
T
E
A
P
Q
Q
Q
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510046
1771
190099
S1002
L
S
Q
L
T
D
A
S
Q
Q
Q
Q
Q
S
P
Chicken
Gallus gallus
XP_414226
1640
175490
S858
L
S
Q
L
T
D
A
S
Q
Q
Q
Q
S
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956189
1415
152530
Q649
T
L
A
T
I
Q
K
Q
D
I
P
S
P
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391906
1265
132547
K499
L
Y
A
V
S
S
G
K
T
S
E
P
H
T
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.5
85.8
91.6
N.A.
74.2
90.3
N.A.
73.2
75.3
N.A.
41.8
N.A.
N.A.
22.9
N.A.
N.A.
Protein Similarity:
100
84.6
86.2
94.4
N.A.
76.9
94.5
N.A.
78.4
83.1
N.A.
55.3
N.A.
N.A.
37.9
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
6.6
20
N.A.
93.3
73.3
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
33.3
33.3
N.A.
100
86.6
N.A.
13.3
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
0
50
0
10
0
0
0
0
10
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
20
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
30
0
10
10
10
20
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
10
% F
% Gly:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
10
0
0
0
20
0
0
0
0
10
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
20
10
0
0
0
0
0
0
0
% K
% Leu:
70
10
10
50
0
10
0
0
0
0
0
0
0
10
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
10
10
10
10
10
0
40
% P
% Gln:
0
0
50
0
10
10
0
10
50
50
60
60
50
20
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
60
20
10
20
10
0
60
0
10
10
10
20
40
20
% S
% Thr:
10
0
0
10
50
0
10
0
10
0
0
0
0
20
0
% T
% Val:
10
0
0
10
0
10
0
0
0
0
0
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _